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OSCAR functions as a collagen I receptor to suppress hippo signaling and reprogram lipid metabolism in clear-cell renal cell carcinoma

作者：Hengyu Shi, Jian Shi, Xuejiao Dong, Songming Wu, Qingyang Lv, Qiangqiang Huang, Daojia Miao, Feiyi Lu, Chengtao Wang, Xiaoping Zhang, Huageng Liang
PMID: 41951612 PMCID: PMC13187165 DOI: 10.1038/s41419-026-08713-1

产品与服务:基因合成

Establishing Komagataella phaffii as a cell factory for efficient production of chondroitin sulfate

作者：Binying Lv, Feng Xiao, Yingjia Pan, Dongfang Li, Jine Li, Chang Dong, Lei Huang, Zhinan Xu, Jiazhang Lian
PMID: 42038006 PMCID: PMC13109340 DOI: 10.1016/j.bidere.2025.100062

产品与服务:基因合成

An orthogonal RNA aptamer for targeted RNA regulation in phase-separated subcellular compartments

作者：Jingcheng Wang, Kaicheng Ma, Xiaomeng Cao, Huirui Wang, Hao Shang, Yinghui Gao, Mengmeng Wang, Wenru Zhang, Kaige Lyu, Yue Dong, Guangkai Luo, Han Yu, Hui Li, Caixing An, Xindan Zhang, Yingying Wu, Jia Ren, Man Li, Ting Dong, Peiyuan Zhang, Xiaohui Liu
PMID: 41851110 PMCID: PMC13150024 DOI: 10.1038/s41467-026-70638-2

产品与服务:基因合成

HHEX-PRKAR2B axis-mediated PKA activation drives glucose metabolism-dependent progression of pancreatic ductal adenocarcinoma

作者：Junxiang Wen, Qiuchen Li, Shuxiang Xu, Wenjun Lu, Fei Wu, Jiatao Lou, Lin Wang
PMID: 41704777 PMCID: PMC12907050 DOI: 10.1016/j.isci.2026.114691

产品与服务:基因合成

Computational and Experimental Verification of Cabozantinib Targeting DDX11 to Inhibit DNA Damage Repair in Liver Cancer

作者：Lianhai Li, Zhenhui Huang, Zhensen Liu, Juxian Zhong, Deliang Li, Liping Liu
PMID: 41696275 PMCID: PMC12902871 DOI: 10.1021/acsomega.5c10093

产品与服务:基因合成

Evolutionary Dampening of Wnt Signaling May Contribute to Naturally Ascrotal Testes in Mammals

作者：Simin Chai, Cuijuan Zhong, Zhenhua Zhang, Daiqing Yin, Shixia Xu, Wenhua Ren, Guang Yang
PMID: 41294232 DOI: 10.1093/molbev/msaf310

产品与服务:基因合成

Macrophage Phospholipase D3 promotes atherosclerosis via exacerbating foam cell formation and inducing inflammatory responses

作者：Teng Li, Xiaobao Gu, Xiangyang Yin, Pengbo Zhai, Hongxu Yan, Zixun Wang, Yang Li, Bing Wang
PMID: 41245776 PMCID: PMC12616045 DOI: 10.1016/j.ijcha.2025.101834

产品与服务:shRNA合成服务

Photoinduced Distance-Dependent Electron Transfer of Fluorescent Proteins

作者：Jianshu Dong, Qian Cao
PMID: 41160877 DOI: 10.1002/cphc.202500021

产品与服务:基因合成

PEDV Nsp14 induces mitophagy-mediated degradation of MAVS to antagonize host innate immunity and facilitate viral proliferation

作者：Lei Yang, Qisheng Qian, Yan-Gang Sun, Xin-Xin Chen, Guangxu Xing, Jia-Qing Zhang, Bao-Song Xing, Songlin Qiao, Rui Li, Gaiping Zhang
PMID: 40631894 PMCID: PMC12363178 DOI: 10.1128/jvi.00498-25

产品与服务:基因合成

Alisol B ameliorated metabolic dysfunction-associated steatotic liver disease via regulating purine metabolism and restoring the gut microbiota disorders

作者：Lin Yiyou, Zhang Congcong, Ren Guilin, Qiu Jiannan, Fu Yilong, Liu Fucai, Liu Qingsheng, Yu Zhiling, Chen Lin, Dou Xiaobing
PMID: 40582207 DOI: 10.1016/j.phymed.2025.156992

产品与服务:XO-过表达质粒

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