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Identification and characterization of a new proline-specific endopeptidase, PvPSE1, from Paecilomyces variotii

作者：Yuzong Liang, Tong Guo, Xiang Gu, Kun Zhong
PMID: 42019642 DOI: 10.1016/j.pep.2026.106933

产品与服务:基因合成

Bridging continuous and discrete evolution through a controllable, hypermutagenic phage-bacteria system

作者：Shujian Ong, Pramila Ghode, Ashvinath Narenderan, Shuxuan Lao, Fabian Willenborg, Tobias V Eden, Carl O Marsh, Wen Shan Yew, Julius Fredens
PMID: 42067623 PMCID: PMC13236587 DOI: 10.1038/s41564-026-02346-y

产品与服务:基因合成

Multi-omics Data Reveal SLC9A3R2 Promotes Breast Cancer Progression and an Immunosuppressive Microenvironment

作者：Zujin Chen, Yao Wang, Guixin Wang, Yue, Xin Wang, Xuchen Cao
PMCID: PMC13189848 PMID: 42179786

产品与服务:基因合成

Fundus albipunctatus disease-associated RDH5/L310delinsEV mutation undertakes AMFR-mediated polyubiquitination and degradation in proteasome

作者：Yichen Dong, Rong Xue, Yi Zhang, Xiaolin Jia, Mingjun Jiang, Mengjiao Xue, Xuyan Peng, Guangming Wan, Yanzhong Hu
PMID: 41679585 DOI: 10.1016/j.exer.2026.110927

产品与服务:基因合成

OSCAR functions as a collagen I receptor to suppress hippo signaling and reprogram lipid metabolism in clear-cell renal cell carcinoma

作者：Hengyu Shi, Jian Shi, Xuejiao Dong, Songming Wu, Qingyang Lv, Qiangqiang Huang, Daojia Miao, Feiyi Lu, Chengtao Wang, Xiaoping Zhang, Huageng Liang
PMID: 41951612 PMCID: PMC13187165 DOI: 10.1038/s41419-026-08713-1

产品与服务:基因合成

Establishing Komagataella phaffii as a cell factory for efficient production of chondroitin sulfate

作者：Binying Lv, Feng Xiao, Yingjia Pan, Dongfang Li, Jine Li, Chang Dong, Lei Huang, Zhinan Xu, Jiazhang Lian
PMID: 42038006 PMCID: PMC13109340 DOI: 10.1016/j.bidere.2025.100062

产品与服务:基因合成

An orthogonal RNA aptamer for targeted RNA regulation in phase-separated subcellular compartments

作者：Jingcheng Wang, Kaicheng Ma, Xiaomeng Cao, Huirui Wang, Hao Shang, Yinghui Gao, Mengmeng Wang, Wenru Zhang, Kaige Lyu, Yue Dong, Guangkai Luo, Han Yu, Hui Li, Caixing An, Xindan Zhang, Yingying Wu, Jia Ren, Man Li, Ting Dong, Peiyuan Zhang, Xiaohui Liu
PMID: 41851110 PMCID: PMC13150024 DOI: 10.1038/s41467-026-70638-2

产品与服务:基因合成

HHEX-PRKAR2B axis-mediated PKA activation drives glucose metabolism-dependent progression of pancreatic ductal adenocarcinoma

作者：Junxiang Wen, Qiuchen Li, Shuxiang Xu, Wenjun Lu, Fei Wu, Jiatao Lou, Lin Wang
PMID: 41704777 PMCID: PMC12907050 DOI: 10.1016/j.isci.2026.114691

产品与服务:基因合成

Computational and Experimental Verification of Cabozantinib Targeting DDX11 to Inhibit DNA Damage Repair in Liver Cancer

作者：Lianhai Li, Zhenhui Huang, Zhensen Liu, Juxian Zhong, Deliang Li, Liping Liu
PMID: 41696275 PMCID: PMC12902871 DOI: 10.1021/acsomega.5c10093

产品与服务:基因合成

Evolutionary Dampening of Wnt Signaling May Contribute to Naturally Ascrotal Testes in Mammals

作者：Simin Chai, Cuijuan Zhong, Zhenhua Zhang, Daiqing Yin, Shixia Xu, Wenhua Ren, Guang Yang
PMID: 41294232 DOI: 10.1093/molbev/msaf310

产品与服务:基因合成

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